After checking out this comic I was like .... "WTF?" & then I thought about it carefully & came to the conclusion it could possibly work. Some insults would then be perfectly acceptable. 'You worthless piece of shit', 'You fucking shit head', 'I shit on you and your children, infidel'. 'Fuck you poo pusher' would be considered a normal task for the homophobic male.
How one could possibly reproduce is a bit of a mystery though.

NSFW
Pros and cons. I'd like to hear yours.
Comments
I guess the human waste management system would be changed or there could be a genetic fuck up that reversed the tubes or a mad doctor might force an anal birth and a vagina poop hole. Actually thinking about it, It can be done. I don't know if the baby would survive or if the mum would make it but dear lord this can work!