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Marijuana Vaporization Study

13371337 Regular
edited July 2010 in Man Cave
A central tenet underlying the use of botanical remedies is that herbs contain many active ingredients. Primary active ingredients may be enhanced by secondary compounds, which act in beneficial synergy. Other herbal constituents may mitigate the side effects of dominant active ingredients. We reviewed the literature concerning medical cannabis and its primary active ingredient, ∆9-tetrahydrocannabinol (THC). Good evidence shows that secondary compounds in cannabis may enhance the beneficial effects of THC. Other cannabinoid and non-cannabinoid compounds in herbal cannabis or its extracts may reduce THC-induced anxiety, cholinergic deficits, and immunosuppression. Cannabis terpenoids and flavonoids may also increase cerebral blood flow, enhance cortical activity, kill respiratory pathogens, and provide anti-inflammatory activity.
Cannabis and Cannabis Extracts: Greater Than the Sum of Their Parts?

This is a good study for a couple of reasons, one, it outlines the effect of the most prominent cannabinoids, terpenoids, and flavonoids individually, as well as how they interact to give a unique medical benefit (high).

Secondly, this study contains a list of all prominent cannabinoids' boiling point, making it VERY useful for cooking or vaporizing.
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  • 13371337 Regular
    edited July 2010
    Here's a summary of the three different tables for easier reference:
    Phytocannabinoids, their boiling points, and properties


    ∆-9-tetrahydrocannabinol (THC)
    Boiling point: 157*C / 314.6 degree Fahrenheit
    Properties: Euphoriant, Analgesic, Antiinflammatory, Antioxidant, Antiemetic

    cannabidiol (CBD)
    Boiling point: 160-180*C / 320-356 degree Fahrenheit
    Properties: Anxiolytic, Analgesic, Antipsychotic, Antiinflammatory, Antioxidant, Antispasmodic

    Cannabinol (CBN)
    Boiling point: 185*C / 365 degree Fahrenheit
    Properties: Oxidation, breakdown, product, Sedative, Antibiotic

    cannabichromene (CBC)
    Boiling point: 220*C / 428 degree Fahrenheit
    Properties: Antiinflammatory, Antibiotic, Antifungal

    cannabigerol (CBG)
    Boiling point: MP52
    Properties: Antiinflammatory, Antibiotic, Antifungal

    ∆-8-tetrahydrocannabinol (∆-8-THC)
    Boiling point: 175-178*C / 347-352.4 degree Fahrenheit
    Properties: Resembles ∆-9-THC, Less psychoactive, More stable Antiemetic

    tetrahydrocannabivarin (THCV)
    Boiling point: < 220*C / <428 degree Fahrenheit
    Properties: Analgesic, Euphoriant



    Terpenoid essential oils, their boiling points, and properties


    ß-myrcene
    Boiling point: 166-168*C / 330.8-334.4 degree Fahrenheit
    Properties: Analgesic. Antiinflammatory, Antibiotic, Antimutagenic

    ß-caryophyllene
    Boiling point: 119*C / 246.2 degree Fahrenheit
    Properties: Antiinflammatory, Cytoprotective (gastric mucosa), Antimalarial

    d-limonene
    Boiling point: 177*C / 350.6 degree Fahrenheit
    Properties: Cannabinoid agonist?, Immune potentiator, Antidepressant, Antimutagenic

    linalool
    Boiling point: 198*C / 388.4 degree Fahrenheit
    Properties: Sedative, Antidepressant, Anxiolytic, Immune potentiator

    pulegone
    Boiling point: 224*C / 435.2 degree Fahrenheit
    Properties: Memory booster?, AChE inhibitor, Sedative, Antipyretic

    1,8-cineole (eucalyptol)
    Boiling point: 176*C / 348.8 degree Fahrenheit
    Properties: AChE inhibitor, Increases cerebral, blood flow, Stimulant, Antibiotic, Antiviral, Antiinflammatory, Antinociceptive

    a-pinene
    Boiling point: 156*C / 312.8 degree Fahrenheit
    Properties: Antiinflammatory, Bronchodilator, Stimulant, Antibiotic, Antineoplastic, AChE inhibitor

    a-terpineol
    Boiling point: 217-218*C / 422.6-424.4 degree Fahrenheit
    Properties: Sedative, Antibiotic, AChE inhibitor, Antioxidant, Antimalarial

    terpineol-4-ol
    Boiling point: 209*C / 408.2 degree Fahrenheit
    Properties: AChE inhibitor. Antibiotic

    p-cymene
    Boiling point: 177*C / 350.6 degree Fahrenheit
    Properties: Antibiotic, Anticandidal, AChE inhibitor



    Flavonoid and phytosterol components, their boiling points, and properties


    apigenin
    Boiling point: 178*C / 352.4 degree Fahrenheit
    Properties: Anxiolytic, Antiinflammatory, Estrogenic

    quercetin
    Boiling point: 250*C / 482 degree Fahrenheit
    Properties: Antioxidant, Antimutagenic, Antiviral, Antineoplastic

    cannflavin A
    Boiling point: 182*C / 359.6 degree Fahrenheit
    Properties: COX inhibitor, LO inhibitor

    ß-sitosterol
    Boiling point: 134*C / 273.2 degree Fahrenheit
    Properties: Antiinflammatory, 5-a-reductase, inhibitor
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  • 13371337 Regular
    edited July 2010
    The tables with the specific vaporization temperatures are good, too, because you can set your vaporizer to specifically release certain cannabinoids. For example, if you want a more euphoric than sedating high, set your vape to 315˚F, to release more THC than CBN, which vapes at 365˚F.
    In a recent study, traces of THC were vaporized at temperatures as low as 140°C (284°F) and the majority of THC vaporized by 185°C (365°F); benzene and other carcinogenic vapors did not appear until 200°C (392°F), and cannabis combustion occurred around 230°C (446°F) (Gieringer 2001).
    Another good piece of information from the study.

    I think it would be worthwhile to do a fractional distillation on marijuana extracts. I know stateofhack was talking about doing one in F&B because someone was getting drug tested for probation. Because the metabolite that is tested for (THC-COOH) occurs after THC metabolism, one could smoke/vaporize only the other cannabinoids and theoretically still pass the drug test. I'm not sure if it ever went past the idea phase, though.
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  • 13371337 Regular
    edited July 2010
    As a corollary to this study, I have found a guide on how to separate CBD - which has anti-inflamitory effects - from other cannabinoids, namely THC.
    Accessing 0.5 to 2.0 Grams CBD Fractionating the Phytocannabinoids by Their Vaporization Points

    Here's more:
    LjPu7.png

    Sorry for the multiple posts, it was going to page stretch either way... Also, sorry for any lack of coherency that occurred while I transferred the posts over from zoklet. Here is the original thread if anyone is interested: http://www.zoklet.net/bbs/showthread.php?t=121784
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  • Anal Probe DeluxeAnal Probe Deluxe Regular
    edited July 2010
    May I add these to the PDF Thread? Source link will be posted. Seriously, these are very, very useful documents. Thank you.
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  • 13371337 Regular
    edited July 2010
    Anal Probe Deluxe wrote: »
    May I add this to the PDF Thread?

    I have no idea what you're talking about but go ahead.
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  • Anal Probe DeluxeAnal Probe Deluxe Regular
    edited July 2010
    1337 wrote: »
    I have no idea what you're talking about but go ahead.

    http://www.totse.info/bbs/showthread.php?t=275

    THANK YOU THANK YOU THANK YoU Also lol at CBD being an anti-psychotic. Oh, the Irony of Reefer Madness!
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  • JustAnotherAssholeJustAnotherAsshole Regular
    edited July 2010
    Fantastic news.
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